Thursday, September 16, 2010

drug

amoxicillin



See available brands of amoxicillin





See related amoxicillin information

Indication
Listed in Dosage.
Dosage
PO Susceptible infections 250-500 mg 8 hrly. Uncomplicated gonorrhoea W/ probenecid: 3 g as a single dose. Dental abscesses 3 g, repeat once 8 hr later. Uncomplicated acute UTI 3 g, repeat once 10-12 hr later. Endocarditis prophylaxis 2 or 3 g as a single dose, 1 hr before dental procedure. Severe or recurrent resp tract infections 3 g twice daily. H.pylori infection W/ either metronidazole or clarithromycin and a bismuth compound or an antisecretory drug: 500 mg 3 times/day. IV/IM Susceptible infections 500 mg 8 hrly. Listerial meningitis W/ other antibiotics: 2 g 4 hrly for 10-14 days.
Click to view Dosage by Indications
Administration
May be taken with or without food. (May be taken w/ meals for better absorption & to reduce GI discomfort.)
Contraindications
Hypersensitivity.
Special Precautions
Renal and hepatic disease; pregnancy, lactation; infectious mononucleosis.
Adverse Drug Reactions
Hyperactivity, agitation, insomnia, dizziness; maculopapular rash, exfoliative dermatitis, urticaria, hypersensitivity vasculitis; diarrhoea, nausea, vomiting; anaemia, thrombocytopenia, leucopenia, agranulocytosis.
Potentially Fatal: Neuromuscular hypersensitivity; pseudomembranous colitis.
Drug Interactions
Increased levels with disulfiram and probenecid. Decreased effects with tetracyclines and chloramphenicol.
Potentially Fatal: Increase effects of oral anticoagulants.
Click to view more Drug Interactions
Pregnancy Category (US FDA)






Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Storage
For special storage condition to ensure optimal shelf-life of medicine... click to view
Mechanism of Action
For details of the mechanism of action, pharmacology and pharmacokinetics and toxicology ... click to view
MIMS Class
Penicillins
ATC Classification
J01CA04 - Amoxicillin; Belongs to the class of penicillins with extended spectrum. Used in the treatment of systemic infections.
Related amoxicillin information:
Drugs interacting with amoxicillin
amoxicillin Patient Med Info
Find amoxicillin in other countries
Search amoxicillin in Google
Search amoxicillin in PubMed

No comments:

Post a Comment