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See related amoxicillin information |
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| Listed in Dosage. |
| PO Susceptible infections 250-500 mg 8 hrly. Uncomplicated gonorrhoea W/ probenecid: 3 g as a single dose. Dental abscesses 3 g, repeat once 8 hr later. Uncomplicated acute UTI 3 g, repeat once 10-12 hr later. Endocarditis prophylaxis 2 or 3 g as a single dose, 1 hr before dental procedure. Severe or recurrent resp tract infections 3 g twice daily. H.pylori infection W/ either metronidazole or clarithromycin and a bismuth compound or an antisecretory drug: 500 mg 3 times/day. IV/IM Susceptible infections 500 mg 8 hrly. Listerial meningitis W/ other antibiotics: 2 g 4 hrly for 10-14 days.
Click to view Dosage by Indications |
| May be taken with or without food. (May be taken w/ meals for better absorption & to reduce GI discomfort.) |
| Hypersensitivity. |
| Renal and hepatic disease; pregnancy, lactation; infectious mononucleosis. |
| Hyperactivity, agitation, insomnia, dizziness; maculopapular rash, exfoliative dermatitis, urticaria, hypersensitivity vasculitis; diarrhoea, nausea, vomiting; anaemia, thrombocytopenia, leucopenia, agranulocytosis.
Potentially Fatal: Neuromuscular hypersensitivity; pseudomembranous colitis. |
| Increased levels with disulfiram and probenecid. Decreased effects with tetracyclines and chloramphenicol.
Potentially Fatal: Increase effects of oral anticoagulants.
Click to view more Drug Interactions |
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Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters). |
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| For special storage condition to ensure optimal shelf-life of medicine... click to view |
| For details of the mechanism of action, pharmacology and pharmacokinetics and toxicology ... click to view |
| Penicillins |
| J01CA04 - Amoxicillin; Belongs to the class of penicillins with extended spectrum. Used in the treatment of systemic infections. |
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