Thursday, September 16, 2010

drug (metronidazole)

Biatron 500® [Film-coated tab]

Pharos
MIMS Class : Other Antibiotics


See related Biatron 500 Film-coated tab information

Contents
Metronidazole
Indications
Urethritis & vaginitis due to Trichomonas vaginalis; amoebiasis due to Entamoeba histolytica. Prophylaxis of post-surgical anaerobe infection. Giardiasis due to Giardia lamblia.
Dosage
Trichomoniasis Adult 2 g daily in a single dose or 500 mg twice daily for 7 days. To prevent re-infection, the partner should be treated simultaneously w/ the same dose. Childn 15 mg/kg body wt/day in 3 divided doses for 7-10 days. Intestinal amoebiasis Adult 750 mg 3 times daily for 5-10 days. Hepatic amoebiasis 500-750 mg 3 times daily for 5-10 days. Childn 35-50 mg/kg body wt/day in 3 times daily for 10 days. Giardiasis Adult 2 g once daily for 3 days or 250-500 mg 3 times daily for 5-7 days. Childn 15 mg/kg body wt in 3 divided doses for 5-7 days. Anaerobe infection Adult 7.5 mg/kg body wt 6 hrly, (Max: 4 g daily) for 7-10 days.
Administration
Should be taken with food
Special Precautions
Pregnancy & lactation. Adjust doses in patients w/ liver dysfunction.
Adverse Drug Reactions
Nausea, anorexia, epigastric pain, metallic taste, vomiting, GI disturbances, urticaria, skin redness, pruritus, angioedema, anaphylaxis.
View ADR Monitoring Form
Pregnancy Category (US FDA)






Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
MIMS Class
Other Antibiotics
ATC Classification
A01AB17 - Metronidazole ; Belongs to the class of local antiinfective and antiseptic preparations. Used in the treatment of diseases of the mouth.
Drug Classification
G
Presentation/Packing
FormPacking/PricePhoto
Biatron 500 Film-coated tablet
Biatron 500 500 mg x 5 x 10's (Rp52250)
Manufacturer:Pharos

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